Flonicamid フロニカミド
Other insecticides: Classes that fit none of the above (phenylpyrazoles, pyridine azomethines and others).
In Japan
- Registration
- Registered as a pesticide (first registered October 6, 2006). 10 formulated products contain it.
- Main registered crops
- melon, apple, Japanese pear, strawberry, cucumber, tomato and others (78 crop names in the registered uses)
- Toxicity class
- Active ingredient: Ordinary substanceClasses of the 10 formulated products (diluted products sold): ordinary substance 10Classes under Japan's Poisonous and Deleterious Substances Control Act.
- ADI (acceptable daily intake)
- 0.073 mg per kg of body weight per day
- ARfD (acute reference dose)
- 3（一般の集団） ／ 1（妊婦又は妊娠している可能性のある女性） mg per kg of body weight
- Evaluation
- Food Safety Commission of Japan, July 20, 2023
ADI: the amount considered to have no effect on health even if eaten every day for a lifetime. ARfD: the amount considered to have no effect on health when eaten at one time (within 24 hours). Both are set by the Food Safety Commission of Japan, mainly from animal studies.
In Japan's national residue testing (fiscal 2024)
| Produce | Detected / tested | Detection rate | Over the limit |
|---|---|---|---|
| DomesticNo. 3 by detection rate | 18 / 359 | 5.0% | 0 |
| ImportedNo. 20 by detection rate | 33 / 1,065 | 3.1% | 1 |
Found in domestic foods: strawberry, cucumber (including gherkin), eggplant, apple, asparagus, tomato, melons (fruit) (max. 0.59 ppm)
Found in imported foods: strawberry, other nightshade (Solanaceae) vegetables, other herbs, okra, tomato, bell pepper, blueberry (max. 2.1 ppm)
Tests are counted as pesticide × sample. Any detection counts as “detected” — it does not mean the limit was exceeded.
In the Consumer Affairs Agency's market basket survey (fiscal 2024; the amount actually taken in from everyday meals), intake was 0.164–0.282% of the ADI.
Evaluations abroad
- WHO acute toxicity class
- II (Moderately hazardous), LD50 884 mg/kgBased on the toxicity of the undiluted active ingredient given once, mainly to rats by mouth (LD50 = the dose that kills half; the smaller, the stronger the acute toxicity). It is not an assessment of the safety of residues in food.
- EU
- Approved in the EU (approval expires November 2026)EU ADI: 0.025 mg/kg bw/day; ARfD: 0.025 mg/kg bw
- IARC (carcinogenicity)
- No matching entry in the IARC list (not evaluated or out of scope, including Group 3)
Related explainers
Sources
- FAMIC (Food and Agricultural Materials Inspection Center), pesticide registration information (as of Sept. 30, 2026) (Japanese)
- Food Safety Commission of Japan, risk assessment report on Flonicamid (July 20, 2023) (Japanese)
- MHLW, results of pesticide residue testing in foods, fiscal 2024 (Japanese)
- Consumer Affairs Agency, daily intake survey of pesticide residues in foods, fiscal 2024 (Japanese)
- WHO Recommended Classification of Pesticides by Hazard 2019
- EU Pesticides Database (Flonicamid (IKI-220))
Last checked 2026-10-01. Registrations and evaluations change over time. This page is a translation of our Japanese page; if they differ, the Japanese page is the reference.