Procymidone プロシミドン
Dicarboximides and others: Classes used against gray mold and similar diseases (procymidone, iprodione, fludioxonil and others).
In Japan
- Registration
- Registered as a pesticide (first registered March 19, 1981). 7 formulated products contain it.
- Main registered crops
- mikan (mandarin orange), cucumber, watermelon, tomato, eggplant, lettuce and others (43 crop names in the registered uses)
- Toxicity class
- Active ingredient: Ordinary substanceClasses of the 7 formulated products (diluted products sold): ordinary substance 7Classes under Japan's Poisonous and Deleterious Substances Control Act.
- ADI (acceptable daily intake)
- 0.035 mg per kg of body weight per day
- ARfD (acute reference dose)
- 0.3（一般の集団） ／ 0.035（妊婦又は妊娠している可能性のある女性） mg per kg of body weight
- Evaluation
- Food Safety Commission of Japan, August 1, 2023
ADI: the amount considered to have no effect on health even if eaten every day for a lifetime. ARfD: the amount considered to have no effect on health when eaten at one time (within 24 hours). Both are set by the Food Safety Commission of Japan, mainly from animal studies.
In Japan's national residue testing (fiscal 2024)
| Produce | Detected / tested | Detection rate | Over the limit |
|---|---|---|---|
| DomesticNo. 18 by detection rate | 93 / 4,755 | 2.0% | 0 |
| Imported | 39 / 4,715 | 0.8% | 3 |
Found in domestic foods: strawberry, cherry (including cherries), kabocha pumpkin (including squash), cucumber (including gherkin), other cucurbit (Cucurbitaceae) vegetables, other Asteraceae vegetables, other nightshade (Solanaceae) vegetables, other vegetables, eggplant, mitsuba (Japanese parsley), cabbage, tomato and others (max. 2 ppm)
Found in imported foods: strawberry, other mushrooms, other nightshade (Solanaceae) vegetables, other Liliaceae vegetables, other fruits, nira (garlic chives), carrot, Welsh onion (including leek), bell pepper, immature peas (max. 1.67 ppm)
Tests are counted as pesticide × sample. Any detection counts as “detected” — it does not mean the limit was exceeded. For pesticides outside the top 20, figures are summed from the food-by-food tables of the full report.
In the Consumer Affairs Agency's market basket survey (fiscal 2024; the amount actually taken in from everyday meals), intake was 0.409–0.477% of the ADI.
Evaluations abroad
- WHO acute toxicity class
- U (Unlikely to present acute hazard in normal use), LD50 6800 mg/kgBased on the toxicity of the undiluted active ingredient given once, mainly to rats by mouth (LD50 = the dose that kills half; the smaller, the stronger the acute toxicity). It is not an assessment of the safety of residues in food.
- EU
- Not approved in the EUEU ADI: 0.0028 mg/kg bw/day; ARfD: 0.012 mg/kg bw
- IARC (carcinogenicity)
- No matching entry in the IARC list (not evaluated or out of scope, including Group 3)
Good to know
- The Food Safety Commission has separately set a lower acute reference dose for pregnant women or women who may be pregnant than for the general population.
Related explainers
Sources
- FAMIC (Food and Agricultural Materials Inspection Center), pesticide registration information (as of Sept. 30, 2026) (Japanese)
- Food Safety Commission of Japan, risk assessment report on Procymidone (August 1, 2023) (Japanese)
- MHLW, results of pesticide residue testing in foods, fiscal 2024 (Japanese)
- Consumer Affairs Agency, daily intake survey of pesticide residues in foods, fiscal 2024 (Japanese)
- WHO Recommended Classification of Pesticides by Hazard 2019
- EU Pesticides Database (Procymidone)
Last checked 2026-10-01. Registrations and evaluations change over time. This page is a translation of our Japanese page; if they differ, the Japanese page is the reference.