Pyrimethanil ピリメタニル

In Japan

Registration

Its registration as a pesticide expired on December 27, 2005 (first registered December 27, 1999). It can no longer be used as a pesticide in Japan.

ADI (acceptable daily intake)

0.17 mg per kg of body weight per day

ARfD (acute reference dose)

not evaluated

Evaluation

Food Safety Commission of Japan, June 7, 2012

ADI: the amount considered to have no effect on health even if eaten every day for a lifetime. ARfD: the amount considered to have no effect on health when eaten at one time (within 24 hours). Both are set by the Food Safety Commission of Japan, mainly from animal studies.

In Japan's national residue testing (fiscal 2024)

Found in domestic foods: corn (maize) (max. 0.06 ppm)

Found in imported foods: strawberry, other citrus fruits, other nightshade (Solanaceae) vegetables, Welsh onion (including leek), grape, orange (including navel orange), grapefruit, banana, blueberry, raspberry, lemon, immature peas and others (max. 3.3 ppm)

Tests are counted as pesticide × sample. Any detection counts as “detected” — it does not mean the limit was exceeded. For pesticides outside the top 20, figures are summed from the food-by-food tables of the full report.

Evaluations abroad

WHO acute toxicity class

III (Slightly hazardous), LD50 4150 mg/kg

Based on the toxicity of the undiluted active ingredient given once, mainly to rats by mouth (LD50 = the dose that kills half; the smaller, the stronger the acute toxicity). It is not an assessment of the safety of residues in food.

EU

Approved in the EU (approval expires April 2041)

EU ADI: 0.013 mg/kg bw/day; ARfD: 1.0 mg/kg bw

IARC (carcinogenicity)

No matching entry in the IARC list (not evaluated or out of scope, including Group 3)

Good to know

• Its registration as a pesticide expired in Japan in 2005, and it is now designated as a food additive used as a postharvest fungicide.

Related explainers

• Most and least toxic pesticides, ranked (acute toxicity, ADI, carcinogenicity)
• Does washing, peeling or boiling remove pesticide residues? Measured results
• How are maximum residue limits set? Japan’s positive list system and how much we actually eat

• Post-harvest pesticides and imported foods

Sources

• FAMIC (Food and Agricultural Materials Inspection Center), pesticide registration information (as of Sept. 30, 2026) (Japanese)
• Food Safety Commission of Japan, risk assessment report on Pyrimethanil (June 7, 2012) (Japanese)
• MHLW, results of pesticide residue testing in foods, fiscal 2024 (Japanese)
• WHO Recommended Classification of Pesticides by Hazard 2019
• EU Pesticides Database (Pyrimethanil)

Last checked 2026-10-01. Registrations and evaluations change over time. This page is a translation of our Japanese page; if they differ, the Japanese page is the reference.

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