日本語
Supplement ingredient databaseChecked 2026-09-30

Hesperidin ヘスペリジン

Foods with Function Claims ingredientClaim not authorised in the EU

A polyphenol found in citrus fruits (such as satsuma mandarins and lemons). Foods with Function Claims mostly use "monoglucosyl hesperidin," a form made more soluble in water.

See example products PR

In Japan: Foods with Function Claims notifications

79notifications (excluding withdrawn)
67with this ingredient alone
37as tablets, capsules, etc.
2016first notification

Functions claimed (counted from notifications with this ingredient alone)

Examples of notified claims (our translation)

This product contains monoglucosyl hesperidin. Monoglucosyl hesperidin has been reported to have the function of improving blood flow (peripheral blood flow) that has decreased due to cold and keeping body temperature (peripheral body temperature).
万田発酵のぽかぽかライフ(万田発酵株式会社) / notification No. J970 / notified 2024-12-27 / processed food (tablets, capsules, etc.)
This product contains lemon-derived monoglucosyl hesperidin. Lemon-derived monoglucosyl hesperidin has been reported to have the function of reducing the temporary feeling of facial puffiness and puffiness in the legs (calves).
グミーナ むくみケア(株式会社モントワール) / notification No. K351 / notified 2025-09-29 / processed food (other)
This product contains immature satsuma mandarin extract. Immature satsuma mandarin extract has been reported to reduce nasal discomfort caused by pollen, house dust, dust, and the like.
青みかんドリンク(株式会社宗新) / notification No. J593 / notified 2024-08-29 / processed food (other)

Cautions written in the notifications (most common)

  • “If you are taking antihypertensive drugs or other medications, consult your doctor or pharmacist.” (6 notifications)
  • “If you are taking anticoagulants, antiplatelet drugs, antihypertensive drugs, or sedatives, consult your doctor or pharmacist.” (4 notifications)
  • “If you are using antihypertensive drugs or other medications, consult your doctor or pharmacist.” (3 notifications)
  • “If you are taking antihypertensive drugs or other medications, consult your doctor or pharmacist.” (2 notifications)
  • “If you experience headache, stomach discomfort, diarrhea, or the like after taking this product, stop using it.” (3 notifications)

Under Foods with Function Claims, the company notifies the Consumer Affairs Agency of the scientific evidence on its own responsibility; the government does not review or approve it. You can look up each product's notification by the number on the package in the Consumer Affairs Agency's database (Japanese).

In Japan: Foods for Specified Health Uses (FOSHU)

12products approved (as of Sept. 1, 2026)
2with sales in fiscal 2024

Approved claims by category: Triglycerides 11, Blood pressure 1

This product contains monoglucosyl hesperidin, which acts to lower blood triglycerides, and is suitable for people who tend to eat fatty meals and people whose blood triglycerides are on the high side.
緑の搾茶(みどりのさくちゃ)(株式会社佐藤園) / ingredient: monoglucosyl hesperidin / powdered soft drink / re-approved FOSHU

FOSHU products are reviewed and approved one by one by the government (Consumer Affairs Agency) for effectiveness and safety. The counts are of products whose functional ingredient matches this ingredient. Source: Consumer Affairs Agency, list of approved FOSHU products (Japanese). Claims are our translation.

In the EU: the register of health claims

Claim not authorised in the EU

  • The "bone" and "LDL cholesterol" claims were not authorised (2010 and 2011 opinions).

In the EU, only health claims whose evidence has been assessed by the European Food Safety Authority (EFSA) and authorised by the European Commission may be used on food. “Not authorised” means the evidence for that claim was not established under EU standards — not that the ingredient is dangerous.

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These are Japanese online shops (affiliate links).

Example of a product notified with this ingredient

中性脂肪サポート (株式会社ファンケル)

Food with Function Claims, notification No. D155. Chosen from products sold on Rakuten whose names match a current notification to the Consumer Affairs Agency, picking one with many reviews.

See on Rakuten (fancl-shop)See on Amazon.co.jp

This database does not guarantee any product's effect. For Foods with Function Claims, check the notification number on the package; for Foods with Nutrient Function Claims, check the amount per daily serving.

Compare “ヘスペリジン サプリ” products on RakutenCompare “ヘスペリジン サプリ” products on Amazon.co.jp
This page lists information published by governments and public bodies. It does not guarantee any effect or judge whether something is good or bad. If you are being treated for an illness, taking medicine, pregnant or breastfeeding, talk to a doctor or pharmacist before use.

Other ingredients in the same categories

This page is a translation of our Japanese page; if they differ, the Japanese page is the reference.

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