日本語
Reading labelsJapan vs. abroadFact checkChecked 2026-10-01

What Is Nam Pla (Fish Sauce)? How It Is Made, How It Differs from Shottsuru, Ishiru, and Ikanago Soy Sauce, and Its Salt and Histamine Checked Against International Standards and Japan's Food Composition Tables

PR This article contains affiliate links to Rakuten Ichiba (“See on Rakuten”). What is written here is based on official sources and published studies, whether or not there is an ad. The “See on Amazon.co.jp” and “See on Yahoo! Shopping” links are also affiliate links.

Nam pla is an essential seasoning in Thai dishes such as gapao and tom yum kung, and in Vietnamese pho. Japan has its own fish sauces too: “shottsuru” from Akita, “ishiru” from Noto, and “ikanago soy sauce” (ikanago shoyu) from Kagawa.

At the same time, you often hear that it “smells strong,” that it is “high in salt,” and that it is “said to be high in histamine.”

This article uses international standards, government sources, Japan’s food composition tables, and studies to check:

  • What fish sauce (nam pla) is made from, and how
  • How nam pla, nuoc mam, shottsuru, ishiru, and ikanago soy sauce differ
  • What the international standard (Codex) and the Thai standard actually set
  • How much more salt it contains than soy sauce
  • How much glutamic acid, the source of umami, it contains
  • What histamine standards exist, and what the actual test values and food poisoning cases look like

Conclusion

  • Fish sauce is a liquid obtained by mixing fish with salt, fermenting and aging it, and straining it. Enzymes already present in the fish’s innards and muscle break proteins down into amino acids (autolysis). The international standard (Codex) says fermentation “usually takes 6 months or more”
  • Nam pla (Thailand) and nuoc mam (Vietnam) are made mainly from anchovies. Shottsuru (Akita) is made from sailfin sandfish (hatahata), ishiru (Noto) from squid innards or sardines, and ikanago soy sauce (Kagawa) from sand lance (ikanago)
  • The Codex fish sauce standard sets, among other things, total nitrogen of at least 10 g per liter, salt of at least 200 g per liter, and histamine of no more than 40 mg per 100 g (= 400 mg/kg). A notification from Thailand’s Ministry of Public Health sets total nitrogen for “genuine fish sauce” at 9 g/L or more and puts a cap on the proportion of glutamic acid
  • In Japan’s food composition tables, the salt equivalent of the four fish sauces is 21.2 to 24.3 g per 100 g, about 1.5 times that of koikuchi (dark) soy sauce (14.5 g)
  • Histamine is detected in fish sauces on the market. In a Tokyo Metropolitan Government survey (55 samples), the highest value was 380 mg/kg, and none exceeded the international standard of 400 mg/kg. Japan has no standard value for histamine in food. The main causes of histamine food poisoning are fish themselves, such as tuna, marlin, and mackerel, and among the sources we checked we found no food poisoning case in which fish sauce was identified as the cause

Products introduced in this article

Within the article, we introduce the following items where they fit the point being made (these are Rakuten Ichiba links).

For people who… Product introduced Why chosen (facts) Where
Want to compare nam pla ingredients メガシェフ ナンプラー (Mega Chef Nam Pla) 200 ml Made in Thailand. The ingredient list (原材料名) reads iwashi (sardine/anchovy-type fish), salt, sugar, and fructose. The Thai-language label on the bottle gives proportions: 70% katakuchi iwashi (anchovy), 27% salt, 2% sugar What the label tells you
Want nam pla with just fish and salt ユウキ ナンプラー (Yuki Nam Pla) 600 g The ingredient list has two items: anchovy (katakuchi iwashi) and salt (from the sales page) What the label tells you
Want to try Japanese fish sauce 諸井醸造 秋田しょっつる ハタハタ100% (Moroi Brewing Akita Shottsuru, 100% Hatahata), カネイシ いしり (Kaneishi Ishiri) Shottsuru is hatahata (from Akita Prefecture) and salt; ishiri is squid (squid innards) and salt If you want to try a Japanese fish sauce

What Is Nam Pla (Fish Sauce)?

Fish sauce (gyosho in Japanese) is a seasoning made by soaking fish or shellfish in salt, fermenting and aging it, and using the liquid that comes out. Nam pla is the Thai name for fish sauce.

The Codex Alimentarius Commission, which sets international food standards (a body created by FAO and WHO), defines fish sauce in its “Standard for Fish Sauce (CXS 302-2011)” as follows.

  • A clear liquid with a salty taste and a fish flavor, obtained from a fermented mixture of fish and salt
  • Other ingredients that help fermentation may be added
  • Fish sauce made by breaking fish down with acid is not covered by this standard

Japan’s food composition tables also group nam pla, shottsuru, ishiru (ishiri), and ikanago soy sauce together as “魚醤油” (fish soy sauce).

How It Is Made

Mix fish and salt, and let it sit for a long time

The method is broadly the same for fish sauce from any country.

  1. Coat fish (whole, or just the innards) with a large amount of salt and pack it into a pot, tank, or barrel
  2. Cover it and leave it for months to years. The fish loses its shape and everything gradually turns to liquid
  3. Strain the liquid and bottle it. Salt water is sometimes added to the remaining fish to extract a second liquid

The Codex “Code of Practice for Fish and Fishery Products” says that weight ratios of fish to salt of 3:1, 5:2, and 3:2 are common, and that, to prevent spoilage and the growth of disease-causing bacteria, the salt concentration should not fall below 20% by weight. It says that natural fermentation in the tropics generally takes 6 to 18 months to reach good quality.

Fish sauce Fish-to-salt ratio (example from the sources) Aging period (example from the sources)
Nam pla (Thailand) 2:1 or 3:1 (traditional method) 12 to 18 months
Nuoc mam (Vietnam) 3:1 (example of a home recipe) About 2 months at home. 12 months or more in factories, and some are aged 18 to 24 months
Shottsuru (Akita) − 1 year or more
Ishiru (Noto) − Several years or so
Ikanago soy sauce (Kagawa) A producer says 25% salt is needed Half a year to 1 year for small sand lance, and 3 years for larger ones, in one example

(Nam pla and nuoc mam are from the book “The Story of Garum,” on ancient fish sauce, and the review by Chan et al. (2023); shottsuru and ishiru are from MAFF’s “Uchi no Kyodo Ryori” (Our Local Dishes); ikanago soy sauce is from an interview survey of Kagawa food culture (2018).)

The enzymes that break down the protein come from the fish itself

The umami of fish sauce comes from the amino acids and peptides formed when fish protein is broken down.

  • The main players are protein-digesting enzymes (proteases) already present in the fish’s innards and muscle. The fish breaks itself down with its own enzymes, which is why this is called “autolysis”
  • Salt-tolerant bacteria (halophilic and halotolerant bacteria) are also involved, and are reported to produce aroma compounds and organic acids
  • A report by the Tokyo Metropolitan Research Laboratory of Public Health (2002) says that fermentation microbes such as koji mold, yeast, and lactic acid bacteria, as used for soy sauce and miso, are not used in making fish soy sauce, and that, because the salt content is also high, protein breakdown is thought to occur mainly through autolysis. However, some shottsuru has koji added, and a Food Safety Commission of Japan document also says “methods using koji and the like are known”

The role of salt

The high salt content of around 20% is there to keep the fish from spoiling.

  • Salt draws out water, making it harder for spoilage bacteria and disease-causing bacteria to grow
  • On the other hand, high salt also weakens the action of the fish’s enzymes, so breakdown proceeds slowly and a long aging period is needed
  • There is research on reducing salt to make it faster, but other measures, such as temperature control, are then needed to keep unwanted bacteria from growing
A diagram showing how fish sauce is made in four steps. Step 1, mix fish and salt and pack them. Weight ratios of fish to salt of 3 to 1, 5 to 2, and 3 to 2 are common, and salt should not fall below 20% by weight. Step 2, cover and let it sit. Natural fermentation in the tropics generally takes 6 to 18 months; shottsuru takes 1 year or more and ishiru several years or so. Step 3, the fish breaks down into liquid. Enzymes already present in the fish’s innards and muscle break protein down into amino acids and peptides (autolysis). Salt-tolerant bacteria produce aroma compounds. Step 4, strain and bottle. Salt water is sometimes added to the remaining fish to extract a second liquid. The role of salt is to make it harder for spoilage bacteria and disease-causing bacteria to grow. It also weakens the fish’s enzymes, so breakdown proceeds slowly. The box below shows the main figures in the Codex fish sauce standard: total nitrogen at least 10 g per liter, amino acid nitrogen at least 40% of total nitrogen, salt at least 200 g per liter, histamine no more than 40 mg per 100 g (400 mg/kg), and fermentation usually 6 months or more.
Figure: How fish sauce is made, and the main figures in the Codex standard (click to enlarge)

How Nam Pla, Nuoc Mam, Shottsuru, Ishiru, and Ikanago Soy Sauce Differ

Name Country / region Main raw material In brief Salt equivalent (per 100 g)
Nam pla Thailand Anchovies and similar fish Thailand’s Ministry of Public Health divides fish sauce into “genuine fish sauce,” “fish sauce made from other animals,” and “mixed fish sauce” 22.9 g
Nuoc mam Vietnam Anchovies and similar fish Phu Quoc Island and Phan Thiet are known as production areas (not in the composition tables)
Shottsuru (塩魚汁) Akita Prefecture Sailfin sandfish (hatahata) Fish are salted and left for 1 year or more until they dissolve. Used in shottsuru hot pot 24.3 g
Ishiru (ishiri) Noto region, Ishikawa Prefecture Innards of Japanese flying squid. Depending on the area, Japanese sardine, round herring, mackerel, or horse mackerel Said to come from “魚汁 (uoshiru),” with the name softening over time. Made since at least the 1700s 21.9 g
Ikanago soy sauce Kagawa Prefecture Sand lance (ikanago) Almost no longer made after the 1950s; efforts to revive it began in the 1990s 21.2 g

(Salt equivalents are from MEXT’s “Standard Tables of Food Composition in Japan 2020 (Eighth Revised Edition), 2023 Supplement.”)

  • MAFF’s “Uchi no Kyodo Ryori” presents ishiru as one of the “three great fish sauces of Japan,” along with Akita’s “shottsuru” and Kagawa’s “ikanago soy sauce”
  • The sailfin sandfish used for shottsuru is caught more off Akita than anywhere else in Japan. To protect the resource, sailfin sandfish fishing was banned entirely from September 1992 to September 1995, and it is said that shottsuru makers also had to stop production
  • Ishiru is said to have been obtained in exchange for rice, to add umami in place of fish in mountain villages in the days when distribution networks did not reach them (MAFF, “Uchi no Kyodo Ryori”)

If you want to try a Japanese fish sauce

We chose two Japanese fish sauces whose only ingredients are fish and salt. Neither has any food additive listed in the ingredient list (原材料名).

International Standards and the Thai Standard

The Codex fish sauce standard (CXS 302-2011)

The Codex standard is an international benchmark that countries use when setting their own food standards. For fish sauce, it sets values such as the following.

Item Standard What it indicates
Total nitrogen At least 10 g per liter (a lower value may be set in some countries) A guide to the amount of protein and amino acids. The more there is, the more has dissolved out of the fish
Amino acid nitrogen At least 40% of total nitrogen The share of protein that has been broken down to amino acids
Salt At least 200 g per liter (as sodium chloride) Prevents spoilage
pH 5.0 to 6.5 for traditional products (4.5 or higher when ingredients that help fermentation are used) How sour it is
Histamine No more than 40 mg per 100 g (= 400 mg/kg) A hygiene standard. No sample may exceed it
Fermentation period Usually 6 months or more A statement in the standard’s definition of the production method
  • The standard says that, if a country requires it, total nitrogen (g/L) may be required on the label, and that terms describing quality by the amount of total nitrogen may be allowed
  • It also specifies the additives that may be used: flavor enhancers (such as monosodium glutamate), sweeteners (acesulfame K, sucralose, aspartame), preservatives (benzoic acid and sorbic acid, up to 1,000 mg per kg), and caramel color (Caramel III, up to 50,000 mg per kg). Whether additives are used differs by product, so check the ingredient list (原材料名) on the back label (our article on caramel color)

The Thai standard (Ministry of Public Health Notification No. 203, 2000)

Thailand sets fish sauce quality by a Ministry of Public Health notification (based on an unofficial English translation).

Item Genuine fish sauce Mixed fish sauce
What it is Obtained by fermenting and breaking down fish or fish parts Genuine fish sauce or the like, with other ingredients added, diluted, or seasoned
Total nitrogen At least 9 g per liter At least 4 g per liter
Amino acid nitrogen 40% to 60% of total nitrogen (not set)
Glutamic acid ÷ total nitrogen 0.4 to 0.6 0.4 to 1.3
Salt At least 200 g per liter (in total, if potassium chloride is used) Same
Color No coloring other than brown sugar or caramel color Same
  • How the product is named is also set. Genuine fish sauce is labeled “genuine fish sauce,” and mixed fish sauce is labeled “mixed fish sauce”
  • Fish sauce made with potassium chloride must carry, in bold red letters, a statement that it contains potassium chloride and is “not suitable for people with kidney disease.” If an artificial sweetener is used, its name must also be shown in bold red letters
  • The 2010 amendment (No. 2) added a requirement that fish sauce to which iodine is added contain 2 to 3 mg of iodine per liter. Fish sauce intended for people who need to limit iodine intake is exempt if this is stated on the label. The notification does not apply to fish sauce made for export (for iodine and the thyroid, see our article on thyroid cancer)

The upper limit on “glutamic acid ÷ total nitrogen” can be read as meant to keep the proportion of glutamic acid in genuine fish sauce within the range that forms naturally from fish. For mixed fish sauce, the upper limit is widened to 1.3.

In the sources we checked, we found no national standard in Japan for the composition of fish sauce (such as total nitrogen). The labeling rules for fish sauce are summarized on the “魚醤” (fish sauce) page of our ingredient dictionary.

What the label tells you

From the label of nam pla sold in Japan, you can learn the ingredient list (原材料名) and the nutrition facts (salt equivalent). Total nitrogen and histamine are not usually given.

Here are nam pla products whose ingredients we have checked on this site, in a form that is easy to compare.

メガシェフ ナンプラー (Mega Chef Nam Pla) ユウキ ナンプラー (Yuki Nam Pla)
Country of manufacture Thailand Thailand
Ingredient list (原材料名) iwashi (sardine/anchovy-type fish), salt, sugar, fructose katakuchi iwashi (anchovy), salt
Proportions shown The Thai-language label on the bottle gives 70% katakuchi iwashi (anchovy), 27% salt, 2% sugar None
Salt equivalent 3.95 g per tablespoon (15 ml) (estimate) 21.6 g per 100 g
Additives listed None None

(For Mega Chef, from the importer’s product page and the Japanese-language label shown in an image posted by Kaldi Coffee Farm; for Yuki, from the Rakuten 24 sales page. Checked September 30 to October 1, 2026.)

Salt Equivalent: About 1.5 Times That of Soy Sauce

Salt equivalent per 100 g of seasoningsSalt equivalent per 100 g of edible portion, from MEXT’s Standard Tables of Food Composition in Japan (Eighth Revised Edition), 2023 Supplement. Shottsuru 24.3 g, nam pla 22.9 g, ishiru (ishiri) 21.9 g, ikanago soy sauce 21.2 g, usukuchi (light) soy sauce 16.0 g, koikuchi (dark) soy sauce 14.5 g, tamari soy sauce 13.0 g, light-colored salty miso 12.4 g, oyster sauce 11.4 g, mentsuyu (3x concentrate) 9.9 g, Worcestershire sauce 8.5 g, koikuchi soy sauce (reduced salt) 8.3 g. The four fish sauces (green) are 21.2 to 24.3 g, about 1.5 times koikuchi soy sauce (14.5 g).Salt equivalent per 100 g (g)Fish sauceOther seasoningsShottsuruFish sauceShottsuru: 24.3 g24.3gNam plaFish sauceNam pla: 22.9 g22.9gIshiru (ishiri)Fish sauceIshiru (ishiri): 21.9 g21.9gIkanago soy sauceFish sauceIkanago soy sauce: 21.2 g21.2gUsukuchi soy sauceUsukuchi soy sauce: 16.0 g16.0gKoikuchi soy sauceKoikuchi soy sauce: 14.5 g14.5gTamari soy sauceTamari soy sauce: 13.0 g13.0gLight salty misoRice misoLight-colored salty miso: 12.4 g12.4gOyster sauceIncludes estimatesOyster sauce: 11.4 g11.4gMentsuyu (3x conc.)Mentsuyu (3x concentrate): 9.9 g9.9gWorcestershire sauceWorcestershire sauce: 8.5 g8.5gKoikuchi, reduced saltKoikuchi soy sauce, reduced salt: 8.3 g8.3gMEXT, Standard Tables of Food Composition in Japan (8th rev.), 2023 Suppl. Values per weight (g)

In the food composition tables, the salt equivalent of the four fish sauces is 21.2 to 24.3 g per 100 g, about 1.5 times that of koikuchi (dark) soy sauce (14.5 g) and higher even than usukuchi (light) soy sauce (16.0 g).

  • On the Mega Chef Nam Pla label, one tablespoon (15 ml) has a salt equivalent of 3.95 g (estimate)
  • The target intake in Japan’s Dietary Reference Intakes (2025 edition) for adults is under 7.5 g for men and under 6.5 g for women (per day). WHO recommends that adults keep salt to under 5 g a day. Details are in our article on salt intake
  • The values in the composition tables are per weight (100 g). Even for the same tablespoon, a liquid seasoning can differ in weight

Ways to use less

Because it is so salty, a small amount is enough to season a dish, which is a feature of fish sauce too. Studies have found the following.

  • Replacing part of the salt with fish sauce: In a US study (Huynh et al. 2016; 70 to 73 tasters per dish), even when sodium chloride was cut by 25% in chicken broth, 16% in tomato sauce, and 10% in coconut curry, liking and flavor intensity did not change much if the difference was made up with fish sauce
  • Changing how it is served: In a study at a university cafeteria in Thailand (Kanchanachitra et al. 2020), serving fish sauce in a small dish with a spoon instead of in a bottle cut the average amount of fish sauce per bowl of noodles sold by 0.25 g, and a special spoon with holes (with an explanation) cut it by 0.58 g. The share of people who added fish sauce did not change, however. The study notes that in Thailand excess salt intake is common and that fish sauce is one of the main sources of salt

The Source of Umami: Glutamic Acid

Glutamic acid per 100 g of seasoningsGlutamic acid per 100 g of edible portion, from Table 1 of MEXT’s Standard Tables of Food Composition in Japan (Eighth Revised Edition), 2023 Supplement, Amino Acids. Tamari soy sauce 2,700 mg, light-colored salty miso 2,200 mg, ikanago soy sauce 1,900 mg, koikuchi (dark) soy sauce 1,600 mg, ishiru (ishiri) 1,500 mg, nam pla 1,300 mg, usukuchi (light) soy sauce 1,300 mg, shottsuru 870 mg. These are amounts measured after hydrolyzing the protein, not only the free glutamic acid that produces umami.Glutamic acid per 100 g (mg)Fish sauceSoy sauce and misoTamari soy sauceTamari soy sauce: 2,700 mg2,700mgLight salty misoRice misoLight-colored salty miso: 2,200 mg2,200mgIkanago soy sauceFish sauceIkanago soy sauce: 1,900 mg1,900mgKoikuchi soy sauceKoikuchi soy sauce: 1,600 mg1,600mgIshiru (ishiri)Fish sauceIshiru (ishiri): 1,500 mg1,500mgNam plaFish sauceNam pla: 1,300 mg1,300mgUsukuchi soy sauceUsukuchi soy sauce: 1,300 mg1,300mgShottsuruFish sauceShottsuru: 870 mg870mgAmino acid tables, Table 1. Measured after hydrolyzing protein (not free glutamic acid only)

Comparing the umami component glutamic acid in the “Amino Acids” tables of the food composition tables, nam pla has 1,300 mg per 100 g, about the same as usukuchi (light) soy sauce and a little less than koikuchi (dark) soy sauce (1,600 mg). Ikanago soy sauce (1,900 mg) and ishiru (1,500 mg) are about the same as koikuchi soy sauce.

There are some cautions in reading these figures.

  • The amino acids in the composition tables are amounts measured after hydrolyzing the protein. What we perceive as umami is “free” glutamic acid, not bound in protein, so the table value does not translate directly into “strength of umami”
  • A study of Italian fish sauce (colatura di Alici) (Corona et al. 2022) cites reports that fish sauce contains about 10 g of amino acids per 100 ml, about 70% of them free. In that study, free glutamic acid in the colatura was 0.56 to 0.73 g per 100 ml
  • A study of Kamakura whitebait (shirasu) fish sauce aged 2 months found 290 mg of glutamic acid per 100 g, and says that fish sauce is also rich in peptides and that glutamic acid alone is not the source of its umami

The Codex standard says “amino acid nitrogen of at least 40% of total nitrogen,” and the Thai standard sets the “proportion of glutamic acid,” because the flavor of fish sauce comes from amino acids.

The difference between umami seasonings labeled “調味料(アミノ酸等)” (seasoning (amino acids, etc.)) and the umami of foods such as fish sauce is sorted out in our article on umami seasonings.

Histamine: Standards, Test Values, and Cases

What is histamine?

Histamine is a chemical that can cause food poisoning (MHLW, FSCJ).

  • It forms when enzymes of bacteria (histamine-producing bacteria) act on histidine, an amino acid abundant in fish. Red-fleshed fish such as tuna, marlin, bonito, mackerel, sardine, saury, yellowtail, and horse mackerel are naturally high in histidine, so histamine builds up if they are handled poorly, for example left at room temperature
  • Histamine is heat-stable, and once formed, it is not broken down by cooking
  • After eating food high in histamine, symptoms such as a flushed face (especially around the mouth and on the earlobes), headache, hives, and fever appear within several minutes to about 30 minutes. It resembles an allergy, but it is food poisoning, not an allergy. Most people recover in 6 to 10 hours
  • The FSCJ says that no deaths have been reported in reports from Japan (notifications from 1998 to 2019), the EU, and the US

The anchovies and sardines used to make fish sauce are also among the fish in which histamine forms easily. A proposed amendment to the Codex code of practice (2018) says that mackerel, sardine, anchovy, and other fish used as raw material for fish sauce carry a risk of histamine formation, and calls for controlling the raw material from aboard the fishing vessel. A Food Safety Commission document also says that histamine “may accumulate” during the production of fermented seasonings.

Histamine standards for fish sauce

Country / organization Histamine standard for fish sauce
Codex Must not exceed 40 mg per 100 g (400 mg/kg)
EU Must not exceed 400 mg/kg (one sample tested per batch)
Canada 200 mg/kg for anchovies, fish sauce, and fermented fish paste
Thailand 200 mg/kg (from a US National Oceanic and Atmospheric Administration survey of national standards)
Japan There is no standard value for histamine in food

(FSCJ “Fact Sheet: Histamine,” 2021; DeBeer et al., “Histamine Limits by Country,” 2021; Codex CXS 302-2011)

  • For fish itself (frozen fish, canned fish, and so on), the standard in both Codex and the EU is 200 mg/kg. For fish sauce and products matured in brine, the value is double that
  • In 2010 Codex carried out a risk assessment of histamine in Thai fish sauce, and found that the risk was about the same at 200 ppm (mg/kg) and at 400 ppm (per the FSCJ fact sheet)
  • Japan has no standard value, but prefectures and other authorities carry out monitoring and guidance of distributed foods and restaurants under the Food Sanitation Act

Test values for fish sauce on the market

Survey Samples Results
Tokyo Metropolitan Research Laboratory of Public Health (2002) 55 fish soy sauce samples bought in Tokyo (41 imported, 14 domestic) For imported products, 75% were under 100 mg/kg, with a maximum of 310 mg/kg. For domestic products, 6 samples had none detected, with a maximum of 380 mg/kg. None exceeded 400 mg/kg
European Food Safety Authority (2011) Foods in Europe Average for fish sauce of 196 to 197 mg/kg
Vietnam (Tran et al. 2020) 21 fish sauce samples bought in Ho Chi Minh City (factory-made and traditional fish sauce) Factory-made fish sauce 8.0 to 80.9 mg/L; traditional fish sauce 385.6 to 1436.4 mg/L. The authors say that, because the amounts used in daily meals are small, histamine poisoning from fish sauce is very rare
Vietnam (Pham et al. 2025) 15 samples of traditional fish sauce, among others Histamine was found in all samples, and some were high, but traditional fish sauce bought at supermarkets was below the EU limit
US, Northern California (Li et al. 2018) 4 samples of fish sauce bought at supermarkets 3 of the 4 samples exceeded either Thailand’s 200 ppm or the EU’s 400 ppm. The authors also write that the amount taken in from fish sauce is very small compared with other fish
  • In the Tokyo survey, domestic fish soy sauce split into two groups: shottsuru made with sailfin sandfish and blended products were low in amines, while ishiru and others made with the innards of sardines, mackerel, and squid were high
  • The same survey also found tyramine, which can raise blood pressure (up to 1,700 µg/g), and the authors say people taking drugs that inhibit the action of monoamine oxidase (MAO) need to be careful

Food poisoning cases

Histamine food poisoning incidents in Japan (2015 to 2025)Incidents reported in MHLW’s “Food Poisoning from Histamine”: patients (bars) and incidents (numbers above the bars). 2015: 13 incidents, 405 patients; 2016: 15 incidents, 283 patients; 2017: 8 incidents, 74 patients; 2018: 20 incidents, 355 patients; 2019: 8 incidents, 228 patients; 2020: 13 incidents, 219 patients; 2021: 4 incidents, 81 patients; 2022: 2 incidents, 148 patients; 2023: 4 incidents, 77 patients; 2024: 8 incidents, 135 patients; 2025: 13 incidents, 431 patients. The main causes were red-fleshed fish such as tuna, marlin, and mackerel and their processed products; in the sources we checked, we found no case in which fish sauce was identified as the cause.Histamine food poisoning (Japan, patients)PatientsAbove bars: number of incidents (cases)1002003004005002015: 13 incidents, 405 patients40513 cases20152016: 15 incidents, 283 patients28315 cases20162017: 8 incidents, 74 patients748 cases20172018: 20 incidents, 355 patients35520 cases20182019: 8 incidents, 228 patients2288 cases20192020: 13 incidents, 219 patients21913 cases20202021: 4 incidents, 81 patients814 cases20212022: 2 incidents, 148 patients1482 cases20222023: 4 incidents, 77 patients774 cases20232024: 8 incidents, 135 patients1358 cases20242025: 13 incidents, 431 patients43113 cases2025Source: MHLW, “Food Poisoning from Histamine”Main cause: red-fleshed fish such as tuna, marlin, and mackerel (NIHS, 2009)No deaths in notifications from 1998 to 2019 (FSCJ)

In Japan, histamine food poisoning is reported every year. In 2025 there were 13 incidents and 431 patients.

  • An analysis by the National Institute of Health Sciences (89 incidents from 1998 to 2008) found that the fish responsible were, in descending order, tuna (33%), marlin (18%), and mackerel (13%), and that about 60% of the dishes were grilled
  • In 2015, 87 people fell ill in a school lunch food poisoning case caused by minced fish (histamine 3,600 to 3,900 mg/kg) that had been handled improperly in distribution. In 2018, 92 people fell ill from a tuna dish (2,300 to 3,600 mg/kg) served in school lunches at a nursery school
  • In the domestic and overseas sources we checked, we found no histamine food poisoning case in which fish sauce was identified as the cause. The EU’s food alert system (RASFF) has 10 notifications about histamine in fish sauce from 1981 to 2020, but these are notifications of products exceeding limits and the like, not counts of food poisoning cases (tuna products over the same period: 444)

Thinking in terms of amount

For histamine, what matters is less “whether it is present” than “how much you take in at one time.”

  • The European Food Safety Authority and the FAO/WHO expert meeting regard up to 50 mg per meal as the no-observed-adverse-effect level for healthy adults. From this and a maximum fish portion of 250 g, FAO/WHO calculated a maximum permissible concentration in fish of 200 mg/kg
  • The authors of the Tokyo survey judged that even eating 100 g of the highest-value fish soy sauce (380 µg/g = 380 mg/kg) would give 38 mg of histamine, and that, used little by little as a seasoning, it would not cause poisoning
  • Urayomi’s calculation: using 15 g of fish sauce at exactly the Codex limit (400 mg/kg) gives 6 mg of histamine
  • However, sensitivity to histamine varies from person to person. The ability to break it down can fall with physical condition, medication, alcohol, and tobacco, and some people have “intolerance,” an inability to break histamine down well (FSCJ)

It cannot be said either that “it is dangerous because it is high in histamine” or that “there is no need to think about it at all.” What we know is that international standards and the EU have a limit for fish sauce (400 mg/kg), that a survey of fish sauce sold in Japanese stores found values within that range, and that most food poisoning is caused by fish themselves that have lost freshness.

Summary

Point What we found Source
How it is made Fish and salt (such as 3:1 by weight, salt 20% or more) are mixed and aged for 6 months or more, mostly 1 year or more. The main players in the breakdown are the fish’s own enzymes Codex standard and code of practice, Tokyo Metropolitan Research Laboratory of Public Health
Types Nam pla (Thailand) and nuoc mam (Vietnam) are from anchovies, shottsuru from sailfin sandfish, ishiru from squid innards or sardines, ikanago soy sauce from sand lance MAFF and others
Standards Codex: total nitrogen 10 g/L or more, salt 200 g/L or more, histamine 400 mg/kg or less. Thailand: genuine fish sauce has total nitrogen of 9 g/L or more and a cap on the proportion of glutamic acid CXS 302-2011, Thai Ministry of Public Health notification
Salt 21.2 to 24.3 g per 100 g. About 1.5 times koikuchi soy sauce Food composition tables
Umami Glutamic acid is 870 to 1,900 mg per 100 g (table values). About the same as soy sauce Food composition tables
Histamine 55 samples from Japanese stores had a maximum of 380 mg/kg, within 400 mg/kg. The main cause of food poisoning is the fish itself, and no case with fish sauce identified as the cause was found Tokyo Metropolitan Research Laboratory of Public Health, MHLW, National Institute of Health Sciences

When choosing fish sauce, what you can check on the label is the ingredient list (原材料名) and the salt equivalent.

  • Some have only fish and salt, and some are seasoned with sugar and the like (comparison of Mega Chef and Yuki)
  • Japanese fish sauces also come with only fish and salt as ingredients (shottsuru and ishiri)
  • Because it is high in salt, the basic approach is not to use it like soy sauce but to add it a little at a time

Note The products introduced here are not presented as being good for your health. Prices and shipping costs may change (shipping varies by region).

Sources

Related articles and databases

This article organizes labeling rules and evaluations based on public agencies' documents and research. It does not judge whether any particular food or additive is safe or dangerous. Rules in Japan and abroad change over time (checked 2026-10-01). This is a translation of our Japanese article; if they differ, the Japanese article is the reference.