日本語
Food additive databaseantioxidantChecked 2026-10-02

Calcium Disodium Ethylenediaminetetraacetate (Calcium Disodium EDTA) エチレンジアミン四酢酸カルシウム二ナトリウム（別名EDTAカルシウム二ナトリウム）

Designated additivePermitted in the EU (E385)EFSA ADI 2.5mg per kg body weight per day
Purpose
antioxidant
On the label
“酸化防止剤（EDTA-Ca・Na）” (antioxidant (EDTA-Ca·Na)), “酸化防止剤（EDTAカルシウムナトリウム）” (antioxidant (EDTA calcium sodium))
Name in the List of Designated Additives
エチレンジアミン四酢酸カルシウム二ナトリウム（別名EDTAカルシウム二ナトリウム） (No. 79)

In Japan

  • Used to prevent oxidation in canned and bottled foods. It may be used only in canned and bottled foods, with upper limits of 0.035 g/kg for soft drinks and 0.25 g/kg for others.
  • Even when disodium EDTA is used, it must be converted to this calcium disodium EDTA before the final food is completed.
  • Because it is an antioxidant, the purpose name is written alongside the substance name, as in “酸化防止剤（EDTA-Ca・Na）” (antioxidant (EDTA-Ca·Na)).

Japan's standards for use

  • Soft drinks in cans or bottles: up to 0.035 g/kg as calcium disodium EDTA
  • Other canned or bottled foods: up to 0.25 g/kg as calcium disodium EDTA
  • May not be used in any other food

This is a summary of the standards for use. See the source list for the exact conditions.

In the EU

  • It is on the EU list of food additives (Regulation (EC) No 1333/2008, Annex II) as E385.
  • In 2024, EFSA issued a call for data for the re-evaluation of E385.
  • In its 2010 evaluation, EFSA (the European Food Safety Authority) set an ADI (acceptable daily intake) of 2.5mg per kg of body weight per day (EFSA ANS).

Sources

Checked 2026-10-02. Rules and evaluations change over time. This page is a translation of our Japanese page; if they differ, the Japanese page is the reference.

This page lists facts stated in laws and in evaluations by public bodies; it is not a safety verdict. Additives used in Japan are approved by the government, which sets the foods and amounts they can be used in. The ADI is a guide to the amount that is considered safe to take every day over a lifetime.

Other substances used as antioxidant

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